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Surgery: Bariatric surgery can help maintain weight by changing the digestive system, such as making the stomach smaller

The handful of studies sometimes cited as human evidence are largely case reports or small, uncontrolled pilot studies

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38 It is known, however, that the major zinc-sensing transcription factors in eukaryotic cells, exemplified by vertebrate MTF-1 and Zap1p in Saccharomyces cerevisiae (Figure 3B) employ one or more ZF motifs as sensors of cellular zinc status, which results in the regulation of transcription of genes that encode enzymes that re-establish zinc homeostasis