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It was placed on the FDAs 503A Category 2 bulk-substances list in September 2023, a designation that restricted its use in pharmacy compounding
J Med Chem 65:876884 Long T, Yang N, Zhou M, Chen D, Li Y, Li J, Tang Y, Liu Z, Li Z et al (2019) Clinical application of 18F-AlF-NOTA-octreotide PET/CT in combination with 18F-FDG PET/CT for imaging neuroendocrine neoplasms
Adding more water after the initial reconstitution is acceptable as long as you maintain sterile technique (alcohol swab, clean syringe)
The presence of an expanded polyQ tract in proteins leads to a self-association that competes with polyQ-mediated interaction with beclin-1 and impairs autophagy in vitro (as observed for ATXN3) and in vivo (as observed for huntingtin), at least in conditions of starvation [85]