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This subtle change affects the peptide's binding affinity to copper ions and its interaction with cellular receptors

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Bombesin-related peptides modulate interleukin-1 production by alveolar macrophages

CCLE expression data were downloaded from KEGG Calcium signaling pathway genes were downloaded from After normalization, Gene Cluster 3.0 with hierarchical clustering for cell lines was used according to Euclidean distance with complete linkage

However, in ME2 homozygously deleted PDAC cell lines, its isoenzyme ME3 plays the compensatory roles for intracellular NADPH homeostasis