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As expected, K47E, K91E, F112A, and H114E mutants showed various degrees of reduction in activation of c-MET (Fig

Although the A/B ratio is used in The Clinic for determining different treatment options, it does not seem to directly correlate with erection grade

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For the cell apoptosis experiment, the ARP1-SRD5A1-KD and H929-SRD5A1-KD cells post 2 g/mL treatment for 48 h at a density of 2 10 5 cells were collected and stained using Annexin-V-Allophycocyanin (Annexin-V-APC) (#640941, BioLegend, San Diego, USA) and PI for 15 min in dark conditions, and the apoptosis of the cells was detected using flow cytometer

Here's the honest answer: it depends