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Another connection is that B6 is involved in the inflammatory signaling pathways in the lungs.[ref][ref][ref] Related article : Asthma, genetic variants, and IL33 inflammation Chronic Low Back Pain: A 2026 clinical trial found that a combination of B12, B1, and B6 was effective at reducing chronic low back pain

Vitamin B12 (also known as cobalamin) is a water-soluble vitamin that plays an important role in metabolism, red blood cell formation, and nerve function

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