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Thus, the synergistic effect of PRMT1 and PRMT5 on SCLC recurrence after chemotherapy may be the result of their joint regulation at both the histone and non-histone levels

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Carpenter EL, Wyant MB, Indra A, Ito S, Wakamatsu K, Merrill GF, et al

The apoptotic index was calculated as the sum of the FITC-Annexin V-positive/PI-negative (early apoptosis) and FITC-Annexin V-positive/PI-positive (late apoptosis) cell populations