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Early human trials in people with obesity found that daily AOD9604 was well tolerated and had a safety profile similar to placebo, with no major effects on glucose metabolism or IGF1, though weightloss results were modest and inconsistent

Some patients prefer injecting on weekdays when they can readily contact their clinical team if questions or concerns arise, particularly during the initial weeks of therapy

These changes typically become visible to others around month two

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Conclusion and perspective Ferroptosis, characterized by iron-dependent lipid peroxidation, presents a unique avenue for targeting cancer cells with specific vulnerabilities