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The apoptosis rate was significantly increased, as well as the release of inflammatory factorsIL-1 and tumor necrosis factor (TNF)- [112]

Per injection: 2 swabs 8 weeks (once daily): ~112 swabs 12 boxes Dosing Protocol A suggested daily titration approach based on common reference doses

E7050: a dual c-met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models

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