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observed a high frequency of promoter hypermethylation and progressive loss of GPx3 expression in Barretts esophagus and its associated lesions, and these authors also confirmed the known function of GPx3 as a potent antioxidant [54]

doi: 10.3389/fphar.2020.566783 Received 29 May 2020 Accepted 25 November 2020 Published 17 December 2020 Volume 11 - 2020 Edited by Lyndy Joy McGaw, University of Pretoria, South Africa Reviewed by Achille Assogbadjo, University of Abomey-Calavi, Benin Pierlorenzo Pallante, Consiglio Nazionale Delle Ricerche (CNR), Italy Updates Copyright 2020 Xiao, Wang, Meng, Liang, Wang, Zhou, Wang, Luo, Gao and Zhang