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Bacterial native amyloid monomeric CsgA protein augmented aggregation of -synuclein proto-fibrils but did not trigger the acceleration of -synuclein monomer to its oligomeric form, as no interaction occurred between CsgA and -synuclein monomer in vitro (Sampson et al., 2020)

34, 35, 36 Further complementing this hypothesis are the observations that hepatic and intestinal permeability markedly increases for transcellular (and paracellular) tracers such as horseradish peroxidase and lanthanum in animals subjected to experimental colitis