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In the presence of specific ferroptosis-inducing agents, baicalein exhibited superior anti-ferroptosis activity compared to established ferroptosis inhibitors such as ferrostatin-1, liproxstatin-1, desferrioxamine mesylate, and -mercaptoethanol (71, 74)

Indeed, rats selectively bred for low intrinsic aerobic capacity display decreased mitochondrial FAO and were predisposed to diet-induced hepatic steatosis [95]

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