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Free Radic Biol Med 152:375385 Zong Y, Li H, Liao P, Chen L, Pan Y, Zheng Y et al (2024) Mitochondrial dysfunction: mechanisms and advances in therapy

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activation of Nrf2, the cellular protective pathway

Mechanisms include: Restoration of endothelial nitric oxide synthase (eNOS) Upregulation of VEGF and FGF-2 (fibroblast growth factor 2) Reduction of oxidative stress and cytokine-induced apoptosis BPC-157 preserved endothelium-dependent vasodilation via upregulation of eNOS and suppression of vascular inflammation. Gwyer Findlay et al., Peptides 4

May be combined with vitamin C or other nutrient IVs to improve absorption and results