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doi: 10.1111/j.1479-828X.2007.00723.x 219 XuYNisenblatVLuCLiRQiaoJZhenXet al
Under pathological conditions, disruption of TFAM can lead to mtDNA mispackaging, a massive release of damaged mtDNA, and down-regulation of TFAM also reduces the stability of the mtDNA mimetic nuclear structure (West et al., 2015)
285 In the absence of oxidative modifications, this binding capability is absent, suggesting that redox modifications can specifically regulate the initiation of biological activities
5 Regulation of adaptive immunity by innate immunity in vitiligo Vitiligo is an autoimmune disease driven by dysregulated adaptive immunity, where autoreactive CD8 + T cells selectively destroy melanocytes, leading to progressive skin depigmentation
Examples include insulin , glucagon , growth hormonereleasing peptides , and many cosmetic or recovery-related peptide products
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