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For instance, a large-scale retrospective cohort study utilizing the Taiwanese National Health Insurance Research Database demonstrated that patients with tinnitus had a significantly higher risk of subsequently developing AD (adjusted hazard ratio 1.54) and PD (adjusted hazard ratio 1.56) over a 10-year follow-up period, positioning tinnitus as a potential soft sign or risk factor for these neurodegenerative conditions (Chu et al., 2020)

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Furthermore, GGCT overexpression reversed the inhibition of miR-29b-3p both in MHCC97H and LNCaP cells (Fig