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The most commonly observed side effects include mild injection-site irritation and nausea, which subside within the first week or two, especially at lower doses

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Proper technique and site rotation are crucial for minimizing discomfort and ensuring optimal absorption

PMCID: PMC5849623 Marini JC, Forlino A, Cabral WA, Barnes AM, San Antonio JD, Milgrom S, Hyland JC, Krkk J, Prockop DJ, De Paepe A, Coucke P, Symoens S, Glorieux FH, Roughley PJ, Lund AM, Kuurila-Svahn K, Hartikka H, Cohn DH, Krakow D, Mottes M, Schwarze U, Chen D, Yang K, Kuslich C, Troendle J, Dalgleish R, Byers PH

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