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To compensate for this, several normalization methods can be applied, including adjustments based on creatinine levels, specific gravity, conductivity, osmolality, or collecting 24-hour urine (Lermen et al

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In humans, data from SARS and Middle East respiratory syndrome also showed that neurological injury in humans is rare, strongly suggesting that, normally, the BBB provides robust neuroprotection from viral CNS invasion in most patients 30