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476 ZIP7 upregulation, on the other hand, hinders the accumulation of PINK1 and Parkin in mitochondria by increasing zinc outflow to the cytosol, contributing to the genesis of myocardial reperfusion injury by inhibiting mitophagy during reperfusion

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In contrast, Drd2 hGFAP cKO mice showed only attenuation of nigral dopaminergic neuron loss induced by MPP + following pyridoxine treatment but not alleviated neuronal damage following quinpirole treatment (Fig

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