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The declining plasma concentration provides a quantitative framework for researchers designing dose-response studies, as physiologically relevant in vitro concentrations should bracket the 200-500 nM range to model the young-to-aged spectrum

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In opiate-dependent patients, small doses of naloxone precipitate a syndrome resembling that produced by opiate withdrawal

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The definition of a Peptide is a molecule that contains two or more amino acids (the molecules that join together to form proteins)