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Upregulation of SLC7A11 increases glutamate output in cells, whereas downregulation of EAAT reduces intracellular glutamate input (Dahlmanns et al., 2023)

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2009 FebApr;30(1-2):4259

This process serves to regulate the promoterenhancer activity, particularly those involving superenhancers, thereby enhancing the transcription of pluripotencyregulating genes and ultimately supporting the maintenance of pluripotency