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1c,ii), but because the sidechain of Tyr78 maintains a network of hydrogen bonds stabilizing the 1-1 loop interactions with helices 2 and 10, mutation to His78 will lead to a disruption of the hydrogen bond network, stability, and dynamics
The combination of energy-modulating drugs is also of interest, with coenzyme Q10 combined with riboflavin or levocarnitine showing greater efficacy in alleviating migraine attacks (86, 99, 100)
In a cross-sectional study, 482 postmenopausal women with diabetes and 482 postmenopausal without diabetes were recruited in a bone health survey
1 2 Ann Intern Med