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GHK-Cu is sensitive to oxidation (the copper ion can participate in undesired redox reactions under suboptimal storage)

showed that PE patients had significantly higher vibratory sensation thresholds for each site as compared with controls using a SMV-5 vibrometer 28

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In mouse studies, spermidine treatment resulted in decreased IL-17 levels in the corneas and lacrimal glands, stabilizing the tear film and mitigating ocular surface inflammation (Lee et al., 2021)