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Rational design using sequence information only produces a peptide that binds to the intrinsically disordered region of p53

Russell-Jones DL, Umpleby AM, Hennessy TR, et al

The compound interacts with Gamma-Aminobutyric Acid (GABA) receptors and influences nitric oxide signaling in neural tissue, providing a measurable protective effect against oxidative stress-induced neuronal damage

Fluctuations in ROS levels can influence the function of protein kinases, phosphatases, and various enzymatic proteins, thereby affecting critical processes such as cellular metabolism, gene regulation, and proliferation [25]