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We also examined its role in inhibiting neuroinflammation by downregulating proinflammatory cytokines in lipopolysaccharide (LPS)-stimulated BV-2 cells

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Tan D-X, Manchester LC, Liu X, Rosales-Corral SA, Acuna-Castroviejo D, Reiter RJ (2013) Mitochondria and chloroplasts as the original sites of melatonin synthesis : a hypothesis related to melatonin s primary function and evolution in eukaryotes