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In contrast, groups treated with arginine and L-carnitine showed significant improvement in all these parameters, suggesting broad neuroprotective action and a protective antioxidant effect

doi:10.1016/s1521-6616(03)00206-7 Simon Gilbody, Sarah Lewis, Tracy Lightfoot, Methylenetetrahydrofolate Reductase ( MTHFR ) Genetic Polymorphisms and Psychiatric Disorders: A HuGE Review, American Journal of Epidemiology , Volume 165, Issue 1, 1 January 2007, Pages 113, Wierzbicki, Anthony S

C.TCA cycle metabolites regulate ROS and reactive nitrogen species, inducing NRF2 activation NRF2 is another major regulator of cellular antioxidant responses

32, 33, 34 Working synergistically with vitamin C, vitamin E mitigates the oxidative stress seen in sleep apnea patients

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