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It upregulates some of the same pathways NAD+ feeds, which is why patients who combine them often report more consistent energy and metabolic improvement than patients on either one alone

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doi: 10.1038/s41420-024-01906-7 40 XuWWangJXuJLiSZhangRShenCet al

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Polyphenolic compounds have also been widely studied for their ability to regulate ferroptosis through the Nrf2 pathway