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The cleavage of GST from the target protein can be challenging, especially if the cleavage site is not efficiently recognized by the protease or if the GST tag affects the accessibility of the cleavage site

Handling & Use Conditions Allow the vial to equilibrate before opening

J Clin Oncol 28:44854491 Wilson P, Anastasaki A, Owen MR, Kempe K, Haddleton DM, Mann SK, Johnston AP, Quinn JF, Whittaker MR et al (2015) Organic arsenicals as efficient and highly specific linkers for protein/peptidepolymer conjugation

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[3] The water itself simply serves as a solvent or vehicle for the drug and does not alter the drugs mechanism of action