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As with other GLP-1 agonists, retatrutide is likely to be unsuitable for those with a family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2

According to NICE CKS guidance on amenorrhoea, low energy availability is a key driver of functional hypothalamic amenorrhoea

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It is interesting that some single-atom metal nanozymes showed stronger GSH peroxidase catalytic activity owing to their large portion of superficial active-site atoms and high atomic utilization efficiency (Kaiser et al., 2020)