Autophagy 17 , 43864400 (2021)
Gastrointestinal effects GLP-1 medications commonly cause nausea, bloating, constipation, and diarrhea
Eryptosis and oxidative damage in diabetes mellitus and its complications Type 2 diabetes mellitus (T2DM) is associated with several long-term complications, including tissue damage and several complex syndromes such as cataracts, renal dysfunction, nerve damage, atherosclerosis, and the shortened lifespan of erythrocytes [306]
GLP-1 can directly bind to the receptors on the surface of -cells in the pancreas, inhibiting the secretion of glucagon from these cells
Finally, the review explores advanced nanodelivery strategies designed to overcome translational barriers and discusses future clinical translation pathways and central challenges