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With the homozygous pGSH1-URA3 strain, a ~ 50% increase of GSH cellular content was observed in cultures supplemented with 100 g/ml 5-FOA, and this increase was relatively stable compared to that of the previous heterozygous strain (Figure S4A)

Lactylation-driven IGF2BP3-mediated serine metabolism reprogramming and RNA m6A-modification promotes lenvatinib resistance in HCC

The maximum recommended dosage is 2 mg once weekly

Glutathione creams are generally well tolerated , with none to minimum side effects reported so far