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In rat models, BPC-157 significantly improved healing of transected Achilles tendons and medial collateral ligaments, supporting its role in soft tissue regeneration. Chang et al., Journal of Orthopaedic Research 4

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10.1038/s41586-021-04369-3 212 YangF.ZhaoK.ZhangX.ZhangJ.XuB

Non-selective c-Met inhibitors include crizotinib (PF-02341066), foretinib (XL-880), cabozantinib (XL-184), glesatinib (MGCD265), BMS-777607, and MK2461, which in addition to c-Met, can inhibit other tyrosine kinases, such as ALK, RON, VEGFR2, KIT, TIE2, PDGFR, VEGFR1, VEGFR3, RET, and FLT-3 [163,164,165], through binding to the ATP binding site on tyrosine kinases