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Many PLP-containing enzymes that catalyze this elimination reaction are syncatalytically inactivated by aminoacrylate intermediate(s) formed during the elimination reaction (Catalytic Mechanism of the Cysteine S-Conjugate -Lyase Reaction and Syncatalytic Inactivation section)

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[13] Allergic responses to glycine itself are exceptionally uncommon

Regulatory bodies work to control the distribution and use of these products, but enforcement challenges remain