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These effects could be more pronounced with concomitant use of hydrocodone bitartrate and acetaminophen tablets and both CYP3A4 and CYP2D6 inhibitors, particularly when an inhibitor is added after a stable dose of hydrocodone bitartrate and acetaminophen tablets is achieved (see WARNINGS)

These findings highlight microglia as promising therapeutic targets at the intersection of neuroinflammation and cardiovascular pathology

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Twenty healthy participants, aged between 20-50 years, without chronic medical conditions, acute illnesses, within the normal BMI range (18.5-24.9 kg/m2), and not regular users of drugs or dietary supplements were enrolled. They were randomly assigned to Group A (liposomal supplementation) or Group B (standard supplementation)