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Patients should be educated about signs and symptoms of potential serious adverse effects, including pancreatitis, gallbladder disease, and severe hypoglycemia if receiving concurrent antidiabetic therapy

It is manufactured in the USA and supplied in a sealed 30 mL vial for reliable storage and shipping

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In a randomized controlled trial, ALA in combination with the antidepressant drug duloxetine, and the anticonvulsant drug pregabalin was shown to effectively treat the symptoms of FM [71, 73]