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10.1371/journal.pone.0018683 72 KomiskiP.HalikP

In all models, the following fixed covariates were entered: assigned treatment (investigational product or placebo), baseline measurement of the outcome of interest, visit (day 14 1 day or day 28 1 day), visit in interaction with treatment, period (period 1 or period 2), sex and, for MIDT outcomes, incentive level

Furthermore, they found that crocetin inhibited ROS generation and increased SOD activity to block inflammation [88]

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