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Christoph Westphal, the chief executive of Sirtris, said of the potential of the drugs, I think that if we are right, this could extend life span by 5 or 10 percent. He added that his goal was to develop drugs against specific diseases, with the extension of life being almost a side effect of our medicine. Sirtris was founded in 2004 after Dr
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doi: 10.1016/j.redox.2021.101901 48 BasuA
However, when this balance is disrupted, homocysteine can reach high levels, associated with an increased risk for cardiovascular disease, neurological disease, and others (Figure 1) [6]