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H&E staining of major organs after treatment revealed no pathological changes

J.KornbluthA.RachmilewitzD.et al (2010)

The downregulation of exosome-derived miR-149-3p contributed to T-helper type 17 (Th17) cell differentiation, promoting intestinal inflammation (Cao et al., 2021)

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4 Hypoxia and metabolic crosstalk in the tumor microenvironment 4.1 Interactions with cancer-associated fibroblasts Hypoxia plays a central role in orchestrating metabolic interactions between cancer cells and stromal components, particularly cancer-associated fibroblasts (CAFs), which are among the most abundant and metabolically active cell types in the TME (127)