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The activation of two transcription factors, aryl hydrocarbon receptor (AhR, which is sensitive to ROS) and hypoxia-inducible factor (HIF)-1, which is responsive to the TCA metabolites succinate, were associated with an increase in IL-22 production

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Simultaneously, BPC-157 upregulates growth hormone receptors in tissue fibroblasts, enhances ERK1/2 signaling for cell proliferation, and activates the FAK-paxillin pathway for cellular adhesion and migration

The phospholipid acyl chain remodeling (Lands cycle) is essential for facilitating ferroptosis through the enrichment of membranes with PUFA [91]