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Nevertheless, we argue that a cytodegeneration of the myelinating unit may be the most proximal event, which could be potentially driven by a protein misfolding mechanism like most other neurodegenerative disorders

Authors and Reviewers Originally written in 2001 by: Jane Higdon, Ph.D

As described previously, GSH has multiple roles in the cell and one of them is functioning as cofactor for the enzyme glutathione peroxidase 4 (GPx4)

The drawbacks of suppositories are relatively minimal, as well

For two of these drugs, risperidone and venlafaxine, the active metabolites (paliperidone and desvenlafaxine, respectively) were marketed as drugs in their own right several years after the parent drugs were marketed