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In the phase 3 REDEFINE 1 trial, the combination of cagrilintide and semaglutide yielded a mean 20% reduction in body weight over 68 weeks in adults with overweight or obesity, significantly outperforming placebo and either agent alone

It is not approved as a personal treatment and is not intended for human consumption, self-administration, veterinary use, diagnosis, or therapeutic application

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Proper dosing requires slow titration to 2.4mg weekly over 12-16 weeks to minimize nausea and GI side effects

Vitamin B1 (Thiamine) It plays an important role in energy metabolism, immunity boosting and functioning of nervous system