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PMID: 40307426 Redox Biol A potential therapeutic strategy based on acute oxidative stress induction for wild-type NRF2/KEAP1 lung squamous cell carcinoma

Most supportive findings come from animal or laboratory studies

Consistent with these findings, while NRF2 induces chemoresistance in KRAS-driven cancers, suppressing glutamine metabolism leads to weakened chemoresistance in these cancer cells 85

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Pernicious Anemia Parenteral vitamin B12 is the recommended treatment and will be required for the remainder of the patient's life