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Melittin inhibits the Toll-like receptors (TLRs) 2,4, CD14, nuclear factor-B essential modulator (NEMO), and Platelet-derived growth factor receptor (PDGFR) signaling pathways

Group 4 received subcutaneous injections of an equivalent volume of saline

TRT has also been reported to increase metabolic rate, which may facilitate fat loss and also protect skeletal musculature against muscle loss during restrictive weight loss diets [15, 16]

This process depletes cellular NAD+ and S-adenosylmethionine (SAM) two critical molecules for energy metabolism and cellular function