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Photographic documentation from month 1 versus month 4 to 6 typically shows measurable differences in density at areas of prior thinning, particularly the temples, crown, and frontal hairline

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Studies have shown that IFN- secreted by cytotoxic T lymphocytes around vitiligo lesions can up-regulate the expression of Hsp70, and Hsp70 can also enhance the release of IFN- by cytotoxic T lymphocytes through a positive feedback mechanism (37)