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Esculetin alleviates pentylenetetrazole-induced seizures, cognitive impairment and pro-inflammatory cytokines and suppresses penicillin-induced epileptiform activity in rats

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doi: 10.1016/j.cmet.2020.06.008 279 FraylingTMBeaumontRNJonesSEYaghootkarHTukeMARuthKSet al

(1997) Structure 5 : 1287-1295 PubMed: 9351803 Search on PubMed DOI: Primary Citation Related Structures: 1AQV, 1AQW, 1AQX PubMed Abstract: Glutathione S-transferases (GSTs) are detoxification enzymes, found in all aerobic organisms, which catalyse the conjugation of glutathione with a wide range of hydrophobic electrophilic substrates, thereby protecting the cell from serious damage caused by electrophilic compounds

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