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Two features of that founding experiment matter enormously and are almost always dropped in summaries
It has been studied for its role in supporting skin appearance and overall skin health for several decades in regenerative medicine literature
Unfortunately, supplementation with DHEA or coenzyme Q10 did not show higher live birth rates (odds ratio: 1.207, 95% confidence interval [CI] = 0.8751.665, P = 0.25) or clinical pregnancy rates (odds ratio: 1.162, 95% CI = 0.9491.424, P = 0.15) compared to women who did not receive supplementation (Figure 7)
Hyponatremia reduces cerebrospinal fluid osmolarity, thereby impairing astrocyte volume regulation and increasing cerebral susceptibility to osmotic stress and ammonia accumulation, ultimately leading to astrocyte swelling [82]