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The duration of the effects varies, spanning from 8 days to 3 weeks , depending on the condition, the specific IV cocktail, and the type of IV Therapy

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Comparing to ADI-PEG20, there are less publications on the anti-cancer mechanisms of pegylated arginase I, but some of the research findings on arginine depletion using ADI-PEG 20 may also be applicable to pegylated arginase I

Cytoreductive removal is also indicated whenever tumour bulk or symptoms threaten organ function