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In some embodiments, a low viscosity otic formulation or device described herein provides an apparent viscosity of from about 100 cP to about 10,000 cP

The pulse radiolysis studies demonstrated that DSePA-mediated radioprotection of in vitro models was due to its ability to directly scavenge the radiolytically generated hydroxyl and peroxyl radicals [82, 83, 85,86,87]