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254 NAD + metabolism programs immunity and inflammation NAD + , along with citrate and succinate, is a novel class of metabolites with inflammatory signaling capacity, linking the NAD + metabolism to the programming of immune responses

Koziel, J., Mydel, P

However, this cytoprotective effect did not translate into improved renal function, as dexamethasone exerted additional ferroptosis-independent effects on innate immune cell recruitment to injured kidneys

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In order to investigate whether the catalytic activity of 3MST is involved in decreasing the level of cysteine and GSH, the effect of 3MST defective mutants were examined