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Neuropathological studies have provided evidence of reduced GABAR levels in the cortex and hippocampus, aberrant GAD1 and GAD2 mRNA expression in the postmortem cortex and cerebellum, and the interneuron markers parvalbumin (PV) and somatostatin (SST) are downregulated

Korean J Chem Eng 27:12461251

Efficacy and safety of co-administered once-weekly cagrilintide 2.4 mg with once-weekly semaglutide 2.4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial

This adaptation enables EAOC cells to survive metabolic stress while simultaneously driving an invasive phenotype

Sep 2016;4(5):857-65