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In summary, our findings offer insights into the neural mechanisms of opioid-induced constipation and help clarify the limited efficacy peripheral opioid receptor antagonists in treating opioid-induced constipation patients

D.DepommierC.DerrienM.EverardA.de VosW

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GHK-Cu at a concentration of 1nM increases the expression of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) in irradiated human dermal fibroblasts, both of which aid blood vessel formation and blood flow into damaged tissues [4- 6]