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We demonstrated that TrkB signalling in these neurons is essential to maintain normal locomotor behaviour consistent with the initial hyperkinetic symptoms of HD and suggested that TrkB signalling deficiency may contribute effectively to HD motor symptoms 13

High insulin level leads to a decrease in sex hormone-binding globulin (SHBG), which leads to an increase of testosterone circulation in blood, resulting in hyperandrogenemia

doi:10.1016/S0968-0004(00)01712-6

Back in the days of Henry VIII, gout was often seen as a disease of the rich

Researchers investigating neuroendocrine pulse architecture have therefore favoured ipamorelin over longer-acting non-peptide analogues when preserving physiological pulsatility is a study design requirement